What could a possible connection be between vaginismus…” That’s hard to pronounce. Constriction of the vagina when there tries to be penetration, essentially is what that is. “And then around four years of interstitial cystitis. What’s the connection between these things? The interstitial cystitis has resolved, but vaginismus has not. No trauma that comes to mind as a possible connection, although I’m realizing these issues are not due to bad luck or chance.” No. “Is there any advice you can give me, a little insight as to what could be going on?